Heading to the mountains for your first high-altitude adventure can be an exciting experience, whether you’re trekking, skiing, or simply soaking in the stunning views. However, if you’re new to high altitudes, you might be concerned about altitude sickness. At our committed travel clinic in Exeter, we’re here to help you stay safe and comfortable by providing expert advice on using altitude sickness medication effectively.
Here’s a comprehensive list of dos and don’ts to guide you as a first-time high-altitude traveller, ensuring you make the most of your journey while minimising the risks of altitude sickness.
Dos of Taking Altitude Sickness Medication
1. Consult a Healthcare Professional Before You Travel
Do seek advice from a pharmacist or GP before starting altitude sickness medication. They can assess your medical history, current medications, and travel plans to recommend the most suitable option for you, such as acetazolamide (Diamox).
2. Start Medication Before Your Ascent
Do begin taking altitude sickness medication 24-48 hours before you start ascending. This allows the medication to build up in your system and helps your body adjust to lower oxygen levels as you climb.
3. Follow the Recommended Dosage
Do adhere to the dosage instructions provided by your healthcare professional or on the medication’s packaging. Typically, acetazolamide is taken twice daily, but your pharmacist will provide specific guidance tailored to your needs.
4. Stay Hydrated
Do drink plenty of water while taking altitude sickness medication. Proper hydration supports acclimatisation and helps prevent side effects like dry mouth, which can sometimes occur with medications like acetazolamide.

5. Combine Medication with Gradual Acclimatisation
Do pair altitude sickness medication with gradual ascents whenever possible. Aim to gain no more than 300–500 metres in altitude per day, and plan rest days to allow your body to adjust naturally.
6. Pack Your Medication in Advance
Do ensure your altitude sickness pills are in your travel kit before leaving home. If travelling abroad, carry a copy of your prescription and keep the medication in its original packaging to avoid issues at customs.
Don’ts of Taking Altitude Sickness Medication
1. Don’t Use Medication as a Substitute for Acclimatisation
Don’t rely solely on altitude sickness medication to prevent symptoms. While it can significantly reduce your risk of acute mountain sickness (AMS), combining it with other preventive measures like gradual ascents and adequate rest is crucial.
2. Don’t Ignore Symptoms of Severe Altitude Sickness
Don’t dismiss symptoms like confusion, severe breathlessness, or difficulty walking. These could indicate high-altitude cerebral oedema (HACE) or high-altitude pulmonary oedema (HAPE), which are medical emergencies. Medication won’t treat these conditions, and immediate descent is necessary.
3. Don’t Stop Taking Medication Prematurely
Don’t discontinue altitude sickness medication too soon. Continue taking it for at least 48 hours after reaching your highest altitude or until symptoms subside, as advised by your healthcare provider.
4. Don’t Drink Alcohol While on Medication
Don’t consume alcohol while taking altitude sickness pills. Alcohol can worsen dehydration and interfere with your body’s ability to acclimatise, counteracting the benefits of the medication.
5. Don’t Share Your Medication
Don’t give your altitude sickness pills to someone else, even if they’re experiencing symptoms. The medication is prescribed based on individual health needs, and taking the wrong dose or type of medication can cause harm.
6. Don’t Take Medication Without Understanding Side Effects
Don’t start altitude sickness medication without being aware of potential side effects, such as tingling in the hands and feet, nausea, or increased urination. These side effects are usually mild and temporary, but it’s important to know what to expect and how to manage them.
Tips for First-Time High-Altitude Travellers
Altitude sickness medication is an excellent tool for preventing and managing AMS, but it’s most effective when used as part of a comprehensive approach to high-altitude travel. Keep these additional tips in mind:
Rest and Listen to Your Body: Avoid overexertion, especially during your first few days at altitude.
Pack a First Aid Kit: Include essentials like pain relievers, rehydration sachets, and plasters in case of minor ailments or injuries.
Know the Signs of AMS: Early symptoms include headaches, nausea, dizziness, and fatigue. Recognising these signs early can help you take action to prevent them from worsening.

Why Altitude Sickness Medication Is Worth Considering
For first-time travellers, using altitude sickness medication can provide peace of mind and significantly reduce the risk of AMS. Whether you’re planning a short ski holiday or a multi-day trekking expedition, medication like acetazolamide allows you to focus on enjoying your adventure rather than worrying about potential health issues.
Even holidaymakers not engaging in extreme activities should consider medication if they’re travelling to high-altitude locations. Places like ski resorts or mountain lodges can still pose risks, especially if you ascend rapidly or have no prior experience at altitude.
Get Expert Advice at Luxtons Pharmacy
At Luxtons Pharmacy, we’re here to help first-time high-altitude travellers prepare for their adventures. Our pharmacists can provide personalised advice on altitude sickness medication, ensuring you feel confident and ready for your trip.
Contact us today to learn more, and let us help you make your high-altitude journey safe, enjoyable, and unforgettable.

This blog was written on behalf of Luxtons Pharmacy by Pharmacy Mentor.
